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In contrast, thrombin-induced surface expression of GPIb was increased significantly by 100 microM PGE1 in normal plasma. These data suggest that the thrombin-induced effects observed in functionally abnormal plasmas are due to abnormalities in other components of the coagulation system rather than to a deficiency of prostacyclin.Functional separation of transmitter and non-transmitter subpopulations of monkey globus pallidus neurons. We recorded extracellularly from 62 cells in the globus pallidus of monkeys during behavioral tasks to determine if there is a functional difference between the transmitter and non-transmitter subpopulations. The non-transmitter subpopulation was identified in each animal by an absence of uptake of [3H]GABA and [3H]glycine, while the transmitter subpopulation was identified by an absence of uptake of [3H]dopamine, [3H]dihydroxyphenylalanine ([3H]DOPA) or [3H]serotonin. The non-transmitter subpopulation accounted for 62.5% of the cell population. 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